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2004 Abstracts and Meeting Agenda

38th Annual Meeting
Hotel Monteleone
New Orleans, Louisiana
October 23, 2004

MODERATOR:James Chodosh, M.D.

7:00 a.m. Abstract 1: A Novel Topical Antiviral Agent, PCL-016 (Picolinic Acid), Inhibits Adenovirus Replication in the Ad5/NZW Rabbit Ocular Model
EG Romanowski, KA Yates, RP Kowalski, FS Mah, YJ Gordon. The Charles T. Campbell Laboratory, University of Pittsburgh, Pittsburgh, PA

7:08 a.m. Abstract 2: An Animal Model of Mycobacteria Infection Under Corneal Flaps for Refractive Surgery
CBD Adan, EH Sato, LB Sousa RS Oliverira, SC Leao, D Freitas. Departments of Ophthalmology and Department of Microbiology, Immunology, and Parasitology, Federal University of Sao Paulo, Brazil

7:16 a.m. Abstract 3: Eliminating Trachoma: Fly Control or Antibiotics?
S Lee1, A Wondu2, M Muluken2, D Lee1, E Yi1, Z Zhou1, V Cevallos1, K Donnallan1, J Chidambaram1, B Gaynor1, J Whitcher1, T Lietman1. 1UCSF Department of Ophthalmology, Proctor Foundation and 2Orbis International, Ethiopia

7:24 a.m. Abstract 4: Passive Immunization Therapy for Experimental Staphylococcal Keratitis
AR Caballero, JT Bush, JJ Dajcs, ME Marquart, BA Thibodeaux, RJ O'Callaghan. LSU Health Sciences Center, Department of Microbiology, New Orleans, Louisiana

7:32 a.m. Abstract 5: LasA Protease as a Therapeutic Agent in Staphylococcal Keratitis
IS Barequet1, Y Pessach2, GJ Ben Simon1, M Safrin1, M Rosner1, E Kessler1
1Goldschleger Eye Institute, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Hashomer, Israel and 2Department of Ophthalmology, SZMC, Jerusalem, Ben Gurion University of the Negev, Israel

7:40 a.m. Abstract 6: Corneal Virulence of Non-Capsular Streptococcus pneumoniae
ME Marquart, JM Reed, RJ O'Callaghan, DO Girgis, CC McCormick, AR Caballero. Department of Microbiology,
Immunology, and Parasitology, Louisiana State University, New Orleans, Louisiana

7:48 a.m. Abstract 7: Combination of Pharamacokinetics and Susceptibility Data as Predictive Indicator of Bacterial Keratitis
DW Stroman1, JJ Dajcs1, R Vidal2, Mridvika2, C Martinez2, BA Thibodeaux3, RJ O'Callaghan3, BA Schlech1. 1Alcon Research, Ltd, Fort Worth, Texas, 2Icon Cusi, Barcelona, Spain, 3LSU Health Sciences Center, New Orleans, Louisiana

7:56 a.m. Abstract 8: Is ZymarTM (gatifloxacin 0.3%) Better Than CiloxanTM or Fortified Tobramycin in the Treatment of Experimental Gram-Negative Keratitis?
FS Mah, RP Kowalski, EG Romanowski, KA Yates, BR Kowalski, YJ Gordon. The Charles T. Campbell Laboratory, University of Pittsburgh, Pittsburgh, PA

8:04 a.m. Abstract 9: Comparison of In-Vitro Sensitivity Rates of the Ophthalmic Fluoroquinolones and Vancomycin Against Propionibacterium acnes Ocular Isolates
M Shah, D Ritterband, TL Kajura, W Perez, D Shapiro, JA Seedor, R Koplin
New York Eye and Ear Infirmary Department of Ophthalmology, New York, New York

8:12 a.m. Abstract 10: Clinical Diagnosis, Isolate Frequency, and Susceptibility Profiles for Community Patients Pretreated with 4th Generation Fluoroquinolones
D Miller, E Alfonso, M Diaz, E Perez. Bascom Palmer Eye Institute, Miami, Florida

8:20 a.m. Abstract 11: Comparison of In-Vitro Resistant Rates of Daptomycin and the Ophthalmic Fluoroquinolones Against Methicillin Resistant Staphylococcus aureus (MRSA) Ocular Isolates
S Meskin, TL Kaiura, M Shah, D Ritterband, D Shapiro, J Seedor. New York Eye and Ear Infirmary Department of Ophthalmology, New York, New York

8:28 a.m. Abstract 12: Non-Invasive Fluorophotometry Assessment of Corneal Epithelial Permeability After Exposure to VigamoxTM or ZymarTM
BE McCarey, HF Edelhauser. Emory Eye Center, Atlanta, Georgia

8:36 a.m. Abstract 13: Assessment of Corneal Toxicity Following Exposure to VigamoxD or ZymarD Using in vivo Confocal Microscopy and ZO-1 Staining
W M Petroll, HD Cavanagh, JV Jester. Department of Ophthalmology, University of Texas Southwestern, Dallas, Texas

8:44 a.m. Abstract 14: In vitro Susceptibilities of Ocular Isolates Coagulase-Negative Staphylococci to Fluoroquinolones in Sao Paulo, Brazil
A Oliveira, AL Hofling-Lima, R Belfort, MF Gayoso. Universidade Federal de Sao Paulo, Departmento de Oftalmologia, Sao Paolo, Brazil

8:52 a.m. Abstract 15: Biofilm Formation by E.faecalis on Intraocular Lens Material
S Kobayakawa1, M Gilmore2. 1Department of Microbiology and Immunology, U. Of Oklahoma, Oklahoma City, Oklahoma 2Department of Ophthalmology, U. Of Oklahoma, Oklahoma City, Oklahoma

9:00 a.m. Abstract 16: A Study of the Effectiveness of Preoperative Antibiotics on the Incidence of Postoperative Endophthalmitis in a Clinical Setting
GM Bohigian. Department of Ophthalmology, Washington University, St Louis, Missouri

9:08 a.m. Abstract 17: Intravitreal VigamoxTM (0.5% Moxifloxacin) is Non-Toxic and Effective in Preventing Endophthalmitis in a NZW Rabbit Model
RP Kowalski, EG Romanowski, FS Mah, KA Yates, YJ Gordon. The Charles T. Campbell Laboratory, University of Pittsburgh, Pittsburgh, PA

9:16 a.m. Abstract 18: Influence of Vancomycin on Adhesion of a Staphylococcus epidermidis Strain Encoding ica Locus to Intraocular Lenses
L Kodjikian1,2,3,4, S Baillif1,2, C Roques6, J Garweg4, J Freney3,5, C Burillon2,3.
1Department of Ophthalmology, Croix-Rousse Hospital, Lyon, France 2Department of Ophthalmology, Edouard Herriot Hospital, Lyon, France 3Laboratory "Biomaterials and Matrix Remodeling", EA 3090, Claude Bernard University Lyon, France 4Department of Ophthalmology, Inselspital, Bern University, Bern, Switzerland 5Department of Microbiology, Institute of Pharmaceutical and Biological Sciences, Lyon, France 6Department of Microbiology, EA 819, Xenobiotics Kenetics, Pharmacy Faculty, Paul Sabatier University, Toulouse, France

9:24 a.m. Abstract 19: Comparison of the Penetration into Aqueous Humor in Humans of Two 4th Generation Fluoroquinolones
JP McCulley, W Shine. University of Texas Southwestern Medical School, Dallas, Texas

9:32 a.m. Abstract 20: Efficacy of Intrastromal Corneal Injection of Natamycin on Experimental Fusarium solani Keratitis in Rabbits
L Barbosa de Sousa, AI Shiguematsu, AS Schellini, OF Gompertz, E Bagagli, CA Padovani. Department of Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil

9:40 a.m. Thygeson Lecture - Pseudomonas aeruginosa: Models and Treatment of the Disease
Linda D. Hazlett, Ph.D.

10:02 a.m. Closing Comments and Awards

10:05 a.m. Adjourn

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