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2017 Agenda and Abstracts | Next >

2017 OMIG Abstract 1

Clinico-Microbiological Profile of Microbial Keratitis
in Human Immunodeficiency Virus (HIV) Infected Patients

Bhupesh Bagga, Ashwanti Kumari
Tej Kohli Cornea Institute, L.V.Prasad Eye Institute, Hyderabad, India


Purpose: To review the epidemiological characteristics, Clinio-microbiological profile and treatment outcomes of keratitis in patients with Human Immunodeficiency virus (HIV) infection

Methods: A retrospective analysis was done for 32 patients who presented between 2004 and 2012 to our Institute with microbial keratitis and HIV.

Results: Of the 32 patients, 27 were males and 5 were females. The mean age at presentation was 36.2 years. Unilateral involvement was the most common presentation (n=31). Only 3 patients had given history of significant trauma to the eye. Underlying ocular predisposing factors were recognized in 16 cases, the most common being prior Herpes zoster ophthalmicus (n=10). Fungus was the most common microbiological agent implicated (n=10). The various fungi implicated were Aspergillus, Candida, Penicillium. Other micro-organisms implicated were Herpes zoster, Herpes simplex virus, Acanthamoeba, Pseudomonas, Proteus mirabilus, Moraxella. Mixed infection was noted in 4 cases. Therapeutic penetrating keratoplasty was done in 4 patients and evisceration in 2 patients.9 patients had perforation of corneal ulcer and 3 patients had recurrence.

Conclusion: Atypical/Rare organisms are implicated in HIV infected patients making it challenging to treat these cases. Increased incidence of HZO and fungus as the most common infection are the two most important observations of our study. Microbial Keratitis should be considered as one of the complications of HIV infection.

Disclosure: N


2017 Agenda and Abstracts | Next >