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2023 OMIG Abstract
Purpose: Corneal receptors respond to mechanical, chemical and polymodal stimuli. Cochet-Bonnet esthesiometer (CB) quantifies only mechanical sensitivity and determines hypo- or normal sensitivity. However, hypersensitivity has not been measured to date. Thus, we aim to assess the efficacy of the non-contact esthesiometer (NCE) compared to the CB in patients diagnosed with ocular surface diseases (OSD) with and without ocular pain.
Methods: A prospective cross-sectional study of patients with OSD, with or without ocular pain used NCE followed by CB in both eyes. NCE protocol started at the lowest air pressure and increased it gradually (levels 1 to 5). Measurements with both devices were concluded upon confirmation of the sensation at the lowest stimuli.??Experiencing sensation with the NCE lowest level was considered to represent hypersensitivity.? Paired Wilcoxon Signed Rank tests compared CB and NCE measurements.
Results: Data included 39 patients (age: 62.72±18.16, 28.2% male). The NCE results [median (IQR)] for OD was 3 (2-3), and for OS 3 (2-3.5), were comparable to CB [median (IQR)] for OD and OS 6 (5-6), 6 (6-6), respectively. NCE level 1 confirmed patients were hypersensitive, which CB was not able to measure differently (=6). Some non-responsive NCE level 5 patients showed positive sensation with CB (<1), suggesting that NCE can not measure severe neurotrophic state. Disclosure:
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