The Charles T. Campbell Eye Microbiology Lab
UPMCUniversity of Pittsburgh Schools of the Health Sciences
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Antibiotic Susceptibility E TEST : Keratitis Conjunctivitis Endophthalmitis

 

Susceptibility* of Bacterial Isolates from Keratitis to Common Antibiotics
(January 1, 2020 through December 31, 2020)

 

Staphylococcus aureus (MIC= ug/ml)

ANTIBIOTIC
#
MIN
Q1
MEDIAN
Q3
MAXIMUM
MIC SUSCEPTIBLE
MIC RESISTANT
VANCOMYCIN
26
0.5
0.75
1.00
1.00
1.50
< 2
> 16
GENTAMICIN
26
0.125
0.19
0.19
0.28
4.00
< 4
> 16
MOXIFLOXACIN
26
0.03
0.09
0.09
3.75
64.00
< 0.5
> 2
CEFOXITIN
26
3.0
4.0
5.0
48.0
512.0
< 4
> 8
CEFAZOLIN
26
0.50
0.75
1.00
4.50
96.00
NS
NS
* Antibiotic susceptibilities are based on serum concentrations and NOT concentrations achieved in the corneal tissue.

(#) = Number of isolates tested. NS= No Standards

 

Pseudomonas aeruginosa (MIC= ug/ml)

ANTIBIOTIC
#
MIN
Q1
MEDIAN
Q3
MAXIMUM
MIC SUSCEPTIBLE
MIC RESISTANT
TOBRAMYCIN
18
0.38
0.938
1.50
2.00
6.00
< 4
> 16
CEFTAZIDIME
18
1.00
1.375
1.50
2.25
4.00
< 8
> 32
CIPROFLOXACIN
18
0.064
0.064
0.10
0.14
1.00
< 0.5
> 2
POLYMYXIN B
18
0.75
1.50
2.00
3.00
6.0
< 2
> 8
* Antibiotic susceptibilities are based on serum concentrations and NOT concentrations achieved in the corneal tissue.

(#) = Number of isolates tested.

 

Coagulase Negative Staphylococcus (MIC= ug/ml)

ANTIBIOTIC
#
MIN
Q1
MEDIAN
Q3
MAXIMUM
MIC SUSCEPTIBLE
MIC RESISTANT
VANCOMYCIN
11
0.75
1.00
1.50
1.50
2.00
< 4
> 32
GENTAMICIN
11
0.03
0.06
0.13
4.00
32.00
< 4
> 16
MOXIFLOXACIN
11
0.09
0.75
4.00
64.00
64.00
< 0.5
> 2
CEFAZOLIN
11
0.38
0.50
2.00
3.00
12.00
NS
NS
* Antibiotic susceptibilities are based on serum concentrations and NOT concentrations achieved in the corneal tissue.

(#) = Number of isolates tested. NS= No Standards

 

Streptococcus viridans (MIC= ug/ml)

ANTIBIOTIC
#
MIN
Q1
MEDIAN
Q3
MAXIMUM
MIC SUSCEPTIBLE
MIC RESISTANT
VANCOMYCIN
10
0.25
0.47
0.50
0.81
2.00
<1
-
GENTAMICIN
4
2.00
2.00
2.0
2.75
3.00
< 4
> 16
MOXIFLOXACIN
10
0.064
0.094
0.125
0.2375
0.38
<1
> 4
CEFAZOLIN
5
0.13
0.19
0.38
8.75
16
NS
NS
* Antibiotic susceptibilities are based on serum concentrations and NOT concentrations achieved in the corneal tissue.

(#) = Number of isolates tested. NS= No Standards

 

Other Gram Positive bacteria (MIC= ug/ml)

ANTIBIOTIC
#
MIN
Q1
MEDIAN
Q3
MAXIMUM
MIC SUSCEPTIBLE
MIC RESISTANT
VANCOMYCIN
4
0.38
0.38
0.44
0.6875
0.75
<1
-
GENTAMICIN
4
0.0
0.5
2.5
72.8
96.0
< 4
> 16
MOXIFLOXACIN
4
0.3
0.3
2.2
49.0
64.0
< 1
> 4
CEFAZOLIN
4
0.06
0.08
0.19
12.06
16
NS
NS
* Antibiotic susceptibilities are based on serum concentrations and NOT concentrations achieved in the corneal tissue.

(#) = Number of isolates tested. NS= No Standards

 

Other Gram Negative bacteria (MIC= ug/ml)

ANTIBIOTIC
#
MIN
Q1
MEDIAN
Q3
MAXIMUM
MIC SUSCEPTIBLE
MIC RESISTANT
TOBRAMYCIN
8
0.25
0.438
1.25
1.875
3.00
< 4
> 16
CEFTAZIDIME
8
0.1
0.1
0.4
1.0
512.0
< 8
> 32
CIPROFLOXACIN
7
0.012
0.023
0.032
3.00
4.00
< 1
> 4
POLYMYXIN B
8
0.00
0.25
1.00
6.38
32.00
< 2
> 8
* Antibiotic susceptibilities are based on serum concentrations and NOT concentrations achieved in the corneal tissue.

(#) = Number of isolates tested.

 

 

Susceptibility* of Bacterial Isolates from Conjunctivitis to Common Antibiotics
(January 1, 2020 through December 31, 2020)

 

Staphylococcus aureus (MIC= ug/ml)

ANTIBIOTIC
#
MIN
Q1
MEDIAN
Q3
MAXIMUM
MIC SUSCEPTIBLE
MIC RESISTANT
MOXIFLOXACIN
24
0.05
0.06
0.09
49.0
64.00
< 0.5
> 2
CEFOXITIN
24
3.0
4.0
5.0
32.0
512.0
< 4
> 8
* Antibiotic susceptibilities are based on serum concentrations and NOT concentrations achieved in the corneal tissue.

(#) = Number of isolates tested. NS= No Standards

 

Other Gram Positive bacteria (MIC= ug/ml)

ANTIBIOTIC
#
MIN
Q1
MEDIAN
Q3
MAXIMUM
MIC SUSCEPTIBLE
MIC RESISTANT
MOXIFLOXACIN
7
0.125
0.19
0.25
0.38
0.50
< 1
> 4
* Antibiotic susceptibilities are based on serum concentrations and NOT concentrations achieved in the corneal tissue.

(#) = Number of isolates tested.

 

Gram Negative bacteria (MIC= ug/ml)

ANTIBIOTIC
#
MIN
Q1
MEDIAN
Q3
MAXIMUM
MIC SUSCEPTIBLE
MIC RESISTANT
TOBRAMYCIN
8
0.75
0.813
1.00
1.50
1.5
< 4
> 16
CIPROFLOXACIN
8
0.008
0.012
0.0315
0.1055
0.63
< 1
> 4
POLYMYXIN B
8
0.00
0.188
0.875
1.375
1.50
< 2
> 8
MOXIFLOXACIN
4
0.047
0.0828
0.19
0.33
0.38
NS
NS
* Antibiotic susceptibilities are based on serum concentrations and NOT concentrations achieved in the corneal tissue.

(#) = Number of isolates tested. NS= No Standards

 

 

Susceptibility* of Bacterial Isolates from Endophthalmitis to Common Antibiotics
(January 1, 2020 through December 31, 2020)

 

Gram Positive bacteria (MIC= ug/ml)

ANTIBIOTIC
#
MIN
Q1
MEDIAN
Q3
MAXIMUM
MIC SUSCEPTIBLE
MIC RESISTANT
VANCOMYCIN
14
0.75
1.00
1.75
2.00
2.00
< 4
> 32
* Antibiotic susceptibilities are based on serum concentrations and NOT concentrations achieved in the corneal tissue.

(#) = Number of isolates tested.

 

 

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