2002
Ocular Microbiology and Immunology Group, Abstract 13
OMIG
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An
Outbreak of Pneumococcal Conjunctivitis on a College Campus
P. Sanchez,1 A Bashir,1 J Turco,1 J Pryor,1 J Schwartzman,1 M Martin,2
C Whitney,2 M Zegans1 1Dartmouth Medical School, 2CDC
Purpose:
To describe the microbiology and clinical features of an outbreak
of pneumococcal conjunctivitis on a college campus involving over
500 students.
Methods:
Data from a consecutive series of conjunctival cultures, a prospective
clinical evaluation and a retrospective survey will be presented.
Results:
Streptococcus pneumoniae was isolated from more than 40% of all
conjunctival specimens submitted for culture by the college health
center during the outbreak. Prospective clinical evaluation of 65
students using a simplified screening protocol revealed that observation
of a red eye at 2 feet, purulent discharge, complete obscuration
of the tarsal blood vessels of the lower eyelid and chemosis were
associated with isolation of S.pneumoniae from eye specimens (p<0.05).
Of 232 students who responded to a survey after the outbreak, 70%
experienced bilateral disease, discomfort was graded as moderate,
and more than 90% received topical antibiotics and noted improvement
in symptoms within 5 days of beginning treatment. Duration of symptoms
ranged from 1 to 60 days; 87% reported that symptoms had resolved
at the time of the survey. More than 90% students received an alcohol
based portable hand sanitizer, however, most used none or less than
25% of the bottle. No permanent ocular sequelae were observed as
a result of this infection. No members of the college health care
center staff developed conjunctivitis.
Conclusions:
A non-encapsulated strain of S. pneumoniae caused a large and disruptive
outbreak of bilateral, purulent conjunctivitis among college students.
A simplified clinical screening protocol was effective at identifying
cases that were culture positive. Most patients experience resolution
of symptoms within 5 days of treatment and no significant ocular
sequelae were noted. Normal infection control practices were effective
at preventing transmission of this organism to health care staff.
OMIG
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