2002
Ocular Microbiology and Immunology Group, Abstract 11
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Increased
Risk of Endophthalmitis in Clear Cornea Cataract Surgery
Snyder, RW M.D., Ph.D., Nedrud, Chad M.D., Twelker, Dan O.D., Ph.D.
University of Arizona Department of Ophthalmology
Purpose:
To determine the relative risk of endophthalmitis in clear cornea
cataract
surgery (CCCS) based on a systematic literature review.
Methods:
A Medline Search of the literature published in English or with
English abstracts between 1990 and 2002 was performed using a combination
of key words. A binomial probability distribution of the average
ophthalmologist seeing zero, 1, or 2 cases of endophthalmitis each
year was calculated based on the estimate of risk for
endophthalmitis when CCCS and scleral tunnel incisions were compared.
Results:
We found 3 large studies (>1,842 cases of CCCS) where the incidence
of endophthalmitis in CCCS was 2.6, 3.3, and 22 times greater than
with a scleral tunnel incision. If the incidence were three times
greater with CCCS an Ophthalmologist doing 300 cases per year would
have a probability of 0.42 of seeing no cases, 0.36 of seeing 1
case, and 0.16 of seeing 2 cases.
Conclusions:
The relative risk of endophthalmitis may be 3 or more times greater
with CCCS. This may be an uncommon occurrence and hence unapparent
for most individual eye surgeons. However, this could account for
4000 or more additional cases of endopthalmitis in the US per year
and warrants attention to determine the risk factors.
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