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2013 OMIG Agenda

Ocular Microbiology and Immunology Group
47th Annual Meeting
Friday November 15th, 2013
Astor Crowne Plaza - New Orleans French Quarter
New Orleans, Louisiana


Moderators: Prashant Garg, MD and Bennie H. Jeng, MD

Click on titles to view abstracts
6:45 a.m. Registration
7:30 a.m. Introduction by Moderators
7:35 a.m.

2012 Harry Hirsch Leiter Award Recipient:
An Update on Boston Keratoprosthesis Infectious Endophthalmitis: Incidence and Prevention
I. Behlau, K.V. Martin, J.N. Martin, R. Walcott-Harris, J. Chodosh, C.H. Dohlman
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA

7:42 a.m.

1. The Epidemiology of Ocular Surface Squamous Neoplasia in a Veterans Affairs Population
Andrew J. McClellan, MD1,2; Allison L. McClellan, OD1; Candido F. Pezon, BS1, Carol L. Karp, MD2, William Feuer, MS2; Anat Galor, MD, MSPH1,2
1Miami Veteran Affairs Medical Center, Miami, FL, USA; 2Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL

7:49 a.m.

2. Corneal and Intraocular Invasion of Ocular Surface Squamous Neoplasia After Intraocular Surgery
Juan C. Murillo, MD1, Anat Galor, MD1, Michael C. Wu, MD2, Natasha K. Kim, MD2, Carol L. Karp, MD1
1Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
2University of Washington School of Medicine, Seattle, WA

7:56 a.m. 3. Superficial Keratectomy, Cautery, Amniotic Membrane Transplant for the Treatment of Painful Bullous Keratopathy in Eyes with Poor Visual Potential
Nabeel Shalabi MD1,2,3, Carol Karp MD2, Hassan Aziz MD2, Bennie H. Jeng MD4,5, Anat Galor MD, MSPH1,2
1
Department of Ophthalmology, Miami Veterans Hospital, Miami, FL, 2Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, 3Faculty of Medicine, Hail University, Hail, Saudi Arabia,
4Department of Ophthalmology and Francis I. Proctor Foundation, University of California San Francisco,
San Francisco, CA, 5Department of Ophthalmology, San Francisco General Hospital, San Francisco, CA
8:03 a.m.

4. BACTEC™ versus Conventional Culture for Diagnosis of Endophthalmitis
M Joag1,2, N Nayak1, G Satpathy1, S Prasad1, A Galor2,3, CL Karp2, P Venkatesh1
1Dr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India; 2Bascom Palmer Eye Institute, University of Miami, Miami, FL; 3Miami Veterans Affairs Medical Center, Miami, FL

8:10 a.m. 5. Torque Teno Virus Associated with Culture Negative Endophthalmitis
Russell N. Van Gelder, MD, PhD1, Aaron Y. Lee, MD, MS2, Lakshmi Akileswaran, PhD1,
Michael D. Tibbetts, MD3, Sunir J. Garg, MD3
1Department of Ophthalmology, University of Washington, Seattle, WA; 2Department of Ophthalmology and Visual Sciences, Washington University, St. Louis, MO; 3Wills Eye Hospital, Thomas Jefferson Medical School, Philadelphia PA
8:17 a.m. 6. Curvularia Endophthalmitis: a 32-Year Review
Aleksandra V. Rachitskaya, MD1, Ashvini K. Reddy, MD1, Darlene Miller, DHSc, MPH1, Janet Davis, MD1, Harry W. Flynn, Jr., MD1, William Smiddy, MD1, Wilfredo Lara, MD2, Selina Lin, MD3, Sander Dubovy, MD1, Thomas A. Albini, MD1
1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL; 2Retina Specialists of South Florida, Miami, FL; 3Kaufman Eye Institute, Zephyrhills, FL
8:24 a.m. 7. The Comparison of Culture Isolation to Validated PCR for the Detection of Acanthamoeba from
Ocular Samples

Regis P. Kowalski, MS, [M]ASCP1, Melissa A. Melan, PhD2, Lisa M. Karenchak, BS1, Leela V. Raju, MD1.
1Ophthalmic Microbiology, 2Molecular Diagnostics, UPMC, and the University of Pittsburgh, Pittsburgh, PA
8:31 a.m. 8. Detection of Anti-Enterovirus Immunoglobulins in Tears Post Acute Hemorrhagic Conjunctivitis
Marlyn P. Langford.  Department of Ophthalmology, Louisiana State University Health Sciences Center, Shreveport, LA
8:38 a.m. 9. (Abstract withdrawn)
8:45 a.m. 10. The Ocular Surface Microbiome: Indigenous Communities Colonize the Healthy Cornea and Conjunctiva
Valery I. Shestopalov1A,B, Nabeel Shalabi1A, Alexander Tuzhikov1A, Anat Galor1A, Onsiri Thanahantee1A, Qunfeng Dong2, Evelyn Toh3, David Nelson3, Lakshmi Akileswaran4, Elena Linerdopoulou4; Darlene Miller1A, Russell N. Van Gelder4, Terrence O’Brien1A
1ABascom Palmer Eye Institute,1BCell Biology and Anatomy Univ. of Miami School of Medicine, Miami, FL;
2Department of Biological Sciences, University of North Texas, Denton, TX; 3Department of Biology, Indiana University, Bloomington, IN; 4Department of Ophthalmology, University of Washington, Seattle, WA
8:52 a.m. 11. Contact Lens Surveillance Cultures in Patients Wearing Bandage Contact Lenses
Tenley N Bower, MD; Divya Narendra; Leela V Raju, MD
Department of Ophthalmology, University of Pittsburgh Medical Center and Charles T. Campbell Eye Microbiology Lab, Pittsburgh, PA
8:59 a.m. 12. Ocular isolates of Pseudomonas aeruginosa Produce the Exopolysaccharide Psl
Amanda Naimie1, Antonio DiGiandomenico2, Robert M.Q. Shanks4, Michael E. Zegans1,3
1Dept. of Microbiology and Immunology, 3Dept. of Surgery (Ophthalmology), Geisel School of Medicine at Dartmouth, Hanover, NH, 2MedImmune LLC, Infectious Diseases/Vaccines, Gaithersburg, MD,
4Dept. of Ophthalmology, Campbell Laboratory, University of Pittsburgh School of Medicine, Pittsburgh, PA
9:06 a.m. 13. Microbial Keratitis and Endophthalmitis after Boston Keratoprosthesis
Kang JJ, Ritterband DC, Shah MK, Wu EI, Koplin R, Seedor JA
New York Eye & Ear Infirmary, New York, NY
9:13 a.m. 14. Biofilm-related Infections of the Boston Keratoprostheses
Irmgard Behlau1,2, Ann S. Tisdale1, Elizabeth Leonard1, Frederick A. Jakobiec1, Joseph Tauber3,
and Claes H. Dohlman1

1Ophthalmology, Massachusetts Eye and Ear Infirmary/Schepens Eye Research Institute, Boston, MA,
2Molecular Biology & Microbiology and Ophthalmology, Tufts University School of Medicine, Boston, MA,
3Tauber Eye Center, Kansas University School of Medicine, Kansas City, MO
9:20 a.m. BREAK
9:35 a.m. 15. Biofilm Forming Capability and Relative Tolerance to Vancomyin of Bacterial Isolates Colonizing the Ocular Surface of Patients with Boston Type 1 Keratoprosthesis
Soledad Cortina1, Sarmad H Jassim1, Juan C Jimenez2, Assraa HJ Jaboori1, Michael J Federle3
1Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, 2Department of Microbiology and Immunology, College of Medicine, University of Illinois at Chicago, 3Department of Medicinal Chemistry and Pharmacology, Center for Pharmaceutical Biotechnology, College of Pharmacy,
University of Illinois at Chicago, Chicago, IL
9:42 a.m. 16. A Model System for Testing the Effect of Biofilms on Drug Diffusion Through Contact Lenses
K.M. Brothers; A. Nau; R.M.Q. Shanks
The Charles T. Campbell Laboratory, UPMC Eye Center, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA
9:49 a.m. 17. The In Vitro and In Vivo Evaluation of RPX-978 (Tigecycline) as an Ocular Antibacterial
EG Romanowski, KA Yates, K O’Connor, TA Kowalski, FS Mah, LV Raju, RMQ Shanks, RP Kowalski.
The Charles T. Campbell Ophthalmic Microbiology Laboratory, UPMC Eye Center, University of Pittsburgh, Pittsburgh, PA
9:56 a.m. 18. When is a Scar a Scar?
Deborah S. Jacobs, MD, and Karen G. Carrasquillo, OD, PhD
Boston Foundation for Sight, Needham, MA
10:03 a.m. 19. Graft Infiltrate After Therapeutic Keratoplasty: Recurrence or New infection?
Sujata Das, MS, FRCS; Batriti Wallang, DO; Savitri Sharma, MD;
L V Prasad Eye Institute, Bhubaneswar, India
10:10 a.m. 20. Post-traumatic Fungal Keratitis Due to Neosartorya udagawae: A Case Report
P.A. Ple-plakon1, C. Gupta1, E. Tu2, S.I. Mian1
1Department of Ophthalmology and Visual Sciences, University of Michigan Kellogg Eye Center, Ann Arbor, MI
2Illinois Eye and Ear Infirmary, University of Illinois - Chicago, Chicago, IL
10:17 a.m. 21. Correlation of In Vitro Antifungal Susceptibility and Treatment Outcome in Patients with
Fusarium Keratitis

Savitri Sharma, MD1; Shreyas Ramamurthy, MS2; Somasheila Murthy, MS2; Swapna Reddy, MD1;
K. Manjulatha, MSc1

1Jhaveri Microbiology Centre, 2Cornea and Anterior Segment Service, L. V. Prasad Eye Institute, Road no. 2, Banjara Hills, Hyderabad, India
10:24 a.m. 22. Patients with Infectious Keratitis Demonstrate Persistent and Long-term Increase in Immune cells and Diminished Subbasal Corneal Nerves After Cessation of Anti-Microbial Therapy— A Laser In Vivo Confocal Microscopy Study
Rodrigo Müller1,2, Andrea Cruzat1,2, Bernardo Cavalcanti1,2, Arsia Jamali1, Roxanna Pourmirzaie1,
Emma Brown1, Joseph B. Ciolino2, Ula V. Jurkunas2, James Chodosh2, Reza Dana2,
Deborah Pavan-Langston2, Pedram Hamrah1,2
1Ocular Surface Imaging Center, 2Cornea Service, Department of Ophthalmology, Massachusetts Eye & Ear Infirmary, Harvard Medical School, Boston, MA
10:31 a.m. 23. Clinical Severity of Dry Eye Disease Correlates with Corneal Immune Cell Alterations as Detected by In Vivo Confocal Microscopy
Ahmad Kheirkhah, MD, Shruti Aggarwal, MD, Bernardo M Cavalcanti, MD, Pedram Hamrah, MD.
Ocular Surface Imaging Center, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology,
Harvard Medical School, Boston, MA
10:38 a.m. 24. Dendritiform Keratopathy Associated with Polyquaternium-1
Jeffrey R. Peterson M.D., PhD., Kirk R. Wilhelmus M.D., PhD., Alice Y.Matoba M.D.
Department of Ophthalmology Cullen Eye Institute, Baylor College of Medicine, Houston, TX
10:45 a.m. 25. Treatment of Active Pseudodendrites in Herpes Zoster Ophthalmicus with Topical
Ganciclovir 0.15% Gel

Shruti Aggarwal M.D., Bernardo M. Cavalcanti M.D., Deborah Pavan-Langston M.D.
Cornea and Refractive Surgery Service. Massachusetts Eye & Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, MA
10:52 a.m. 26. Is Zoster Predominately a Disease of Caucasians? An Analysis of Racial Demographics at the University of Chicago
Ashley Rohr, MD, Michael Saidel, MD
University of Chicago Section of Ophthalmology and Visual Science, Chicago, IL
10:59 a.m. 27. The Shingles Vaccine and Other Factors for Earlier Onset Age of Herpes Zoster
Annie Chan, MD,1 Christopher D. Conrady, PhD,1 Kai Ding, PhD,2 and Donald U. Stone, MD1
1Department of Ophthalmology, Dean McGee Eye Institute. 2Department of Biostatistics, University of Oklahoma Health Sciences Center, Oklahoma City, OK
11:10 a.m.

Thygeson Lecture:
Understanding Epidemic Bacterial Conjunctivitis through Comparative Genomics

Michael Gilmore, PhD, Sir William Osler Professor, Harvard Medical School, Department of Ophthalmology, and Department of Microbiology and Immunobiology, Member, Biological and Biomedical Sciences Program, Harvard Medical School, Member, Microbial Sciences Initiative, Harvard University, Associate, Broad Institute of MIT and Harvard

11:50 a.m. Closing Comments and Awards
12:15 p.m.

Business Luncheon, Astor Toulouse B

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